T-cell activation: a multidimensional signaling network.
نویسندگان
چکیده
Naïve T cell activation requires the interactions of antigen receptors, adhesion molecules and co-stimulatory molecules. Antigen receptors and adhesion molecules are involved in spatio-temporal movement to form a stable immunological synapse. This stable junction interrupts T cell migration, and provides a platform for temporally regulated co-stimulatory receptor signaling spanning a period of days.
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ورودعنوان ژورنال:
- Current opinion in cell biology
دوره 14 5 شماره
صفحات -
تاریخ انتشار 2002